AUTOGENOUS IMMUNITY TO ENDOGENOUS RNA TUMOR VIRUS
نویسندگان
چکیده
منابع مشابه
Autogenous Immunity to Endogenous Rna Tumor Virus
The radioimmune precipitation assay using (3)H-labeled AKR leukemia virus was applied to the detection and quantitation of natural serum antibodies directed against endogenous murine leukemia virus (MuLV) envelope antigens B6C3F(1) and BALB/c mice, which have low natural incidences of leukemia and lymphoma, and AKR mice, which have a high incidence, were used in this study. Sera from mice of va...
متن کاملAutogenous Immunity to Endogenous RNA Tumor Virus: Humoral Immune Response to Virus Envelope Antigens
Autogenous immune sera from several strains of mice have been examined for type-, group-, or interspecies-specific reactivities against leukemia virus envelope antigens and virus-induced cell surface proteins. The natural antibody of these test sera react with gp69/71, gp43, and p15 structural components on murine leukemia viruses including AKR, Friend, Rauscher, Moloney, and xenotropic BALB:vi...
متن کاملAutogenous immunity to endogenous RNA tumor virus: humoral immune response to virus envelope antigens.
Autogenous immune sera from several strains of mice have been examined for type-, group-, or interspecies-specific reactivities against leukemia virus envelope antigens and virus-induced cell surface proteins. The natural antibody of these test sera react with gp69/71, gp43, and p15 structural components on murine leukemia viruses including AKR, Friend, Rauscher, Moloney, and xenotropic BALB:vi...
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The autogenous humoral immune response of mice to their endogenous leukemia virus has been examined in terms of the reactivities of individual classes of antibody present in normal B6C3F(1) serum. Whole serum and the immunoglobulin (Ig) M and IgG fractions of serum from animals of different age groups were compared by radioimmune precipitation assays and viral infectivity neutralization assays....
متن کاملAutogenous immunity to endogenous RNA tumor virus antigens in mice with a low natural incidence of lymphoma.
The immune reactivity to endogenous (wild-type) RNA tumor virus-related antigen(s) was evaluated in RF mice, a strain with a low natural incidence of lymphoma. The purposes were to determine whether maintained humoral immunity could be detected and to evaluate the response with respect to the immune-mediated pathogenesis of glomerulosclerosis and incidence of tumors of lymphatic origin. Measure...
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ژورنال
عنوان ژورنال: Journal of Experimental Medicine
سال: 1973
ISSN: 1540-9538,0022-1007
DOI: 10.1084/jem.138.1.194